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looking for advice
Started by Glenn Samuels
Posted: May 31, 2008 at 18:42
my uncle was admitted to hospital with symptoms that turned out to be Staphylococcus aureus (i believe)

he has been in hospital 6 weeks & endured aprox 6 operations on his knee trying to flush/rid him of the infection.

he has had iv antibiotics etc but the infection just doesnt seem to be clearing totally.

he has now been told that there is now a battle to save his leg (amputation has been mentioned if things do not improve)

as you can imagine he is horrified.

any comments of advice or names/contact info on specalist consultants in this field or even perhaps some new treatments available would be very much appreciated.

please leave replies or contact me direct at

many thanks
Re: looking for advice
Reply #1 by Nancy R
Posted: June 1, 2008 at 01:26
Hi Glenn:

If your relative had any type of implant (knee or hip for example), it must be removed before the infection will heal. MRSA LOVES to cling to artificial joints. It happened to me and many others. Once the prosthetic was removed, an antibiotic filled spacer implanted and IV antibiotics administered, the infection finally halted. Then, they removed the spacer and finally put in a new hip prosthetic. I am now doing very, very well with no MRSA symptoms.

You don't say exactly what the surgery entailed. And, the antibiotics that worked for me were IV Daptomycin and oral Bactrin. Vancomycin couldn't be used because I am highly allergic to it and Zyvox failed after many, many weeks of infusion. Cleaning out the joint, finding the right antibiotics and using some vitamin supplements and a better diet made all of the difference in my outcome.

And, I just had another joint replaced 12 May, 2008, just 8 months after the hip replacement. Still no signs of MRSA.
Re: looking for advice
Reply #2 by glenn
Posted: June 2, 2008 at 20:38
thanks for your reply.

he has no implants. he has got some drianage tubes in his knee

the reason for his admittance to hospital was because he contracted Staphylococcus Aureus.
Re: looking for advice
Reply #3 by Nancy R
Posted: June 5, 2008 at 10:03

Just for the record, MRSA is a very specific Staph Aureus. It is Methicillin Resistant Staph Aureus. In other words, staph aureus alone is usually not a big deal. Many antibiotics are effective. MRSA and VRSA are the ones that are making everyone so darn sick. Vancomycin Resistant Staph Aureus is exactly what its name implies. When entire groups of antibiotics become useless, we are left with bacteria that is uncontrollable. It sounds to me like the antibiotics currently being administered are not killing the bug. I live in the States and my doctor, Ronald Delanois and his associate, Michael Mont, are considered to be the best in the world. The are located in Baltimore, Maryland and operate out of Sinai Hospital. Dr. Mont is Johns Hopkins trained and considered to be a pioneer in difficult infected joint replacements.

If you are in the UK, I really don't know what to advise. I'm not familiar with your health care system and totally clueless about private practice there.Perhaps others will check in.

Re: looking for advice
Reply #4 by Maria
Posted: June 6, 2008 at 23:25
Dear Glen
If your uncle is not responding well to the antibiotics then this should be reviewed, and different medication given. The staff should be willing to discuss this with you, with your uncle's permission as they do take patient confidentiality into account.

I don't know where you are located Glen, but there are statistics available on the performance of hospitals in terms of surgical site infections for orthopaedic surgery, therefore this could go someway to help choose a 'safer' hospital in which to have surgery. There is a lot a data that you can look at on Doctor Foster too, amalgamating the information could help with a decision on where to go for further surgery if needed and if we can help you with this then please email us at

In terms of the actual treatment of the infection your uncle has now, this will need discussing with the team looking after him. The Infection Prevention and Control Team should be looking at the antibiotics and liaising with the antimicrobial pharmacist to assess the best treatment for your uncle - although not all hospitals have them. Again this kind of information can be found on the Doctor Foster website. We have a link to this on the left hand menue of our home page and you search by postcode to find out about hospitals near you, both NHS and private our website address is

Do get in touch if we can be of further help, best wishes
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